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The final score is the correct number of substitutions in 90 seconds, and scores range between 0 and Only the written response format of the SDMT was administered. The results of the regression analysis were used to assess the optimal age and education subgroups for norms generation, identify exclusions, and investigate if non- exclusionary health conditions were associated with lower SDMT scores.

Interaction terms between gender, educational attainment, and age were also tested. The population to which the SDMT norms reported in this paper relate are people aged 15 and over living in private dwellings, excluding very remote parts of Australia. Population survey weights provided with the HILDA Survey dataset adjust for selection probabilities and attrition bias to enhance the comparability of the data to the Australian population. As the SDMT was one part of the overall interview, we made a further adjustment to these weights to account for non- completion of the SDMT, adjusting for those who did not commence the SDMT or did not complete it unassisted.

The non-response adjusted individual weight was multiplied by the inverse of the SMDT response propensity, giving higher weight to the participants who completed the SDMT and had similar characteristics to those who did not complete the SDMT. SDMT norms were calculated as weighted means, standard deviations SD , and quintiles stratified by gender, age-group, and education level.

Overall, the mean SDMT was The distributional shape was relatively stable across all subgroups. The results from linear regression analysis are presented in Table 2. Scores on the SDMT were relatively stable through to age 35, after which they declined with increasing age, with age differences becoming more pronounced after age When age was modelled as a continuous variable there were significant quadratic and cubic age trends results not reported.

On average, scores were lower among respondents from non-English speaking backgrounds compared to native English speakers, and Aboriginal or Torres Strait islanders compared to non-Indigenous Australians, but were higher for females compared to males.

Of the health conditions considered as exclusion criteria, self-reported sight problems not corrected by lenses, blackouts, fits and loss of consciousness, learning difficulties, and brain injury or stroke all predicted lower SDMT scores. Lower scores on the SDMT were also independently associated with speech problems, self-reported mental illness, nervous or emotional conditions, breathing difficulties, limited use of legs or feet, restrictive conditions requiring medication, and other unspecified health conditions, but these were not considered a-priori reasons for exclusion from the published norms.

There was evidence of a two-way interaction between gender and education: the gradient in SDMT scores across levels of educational attainment i.

To further investigate this, analysis of the sample stratified by year age groups indicated that the interaction between gender and education was only evident in the mid-age and older age cohorts.

Thus, there was no gender difference in the association between educational attainment and SDMT scores among respondents less than 30 years of age Supplementary Table 2. After all exclusions, we calculated norms from 14, participants. The remaining three tables present the normative data for the SDMT, by key characteristics. Tables 3 and 4 show the cell counts, weighted means and SDs stratified by age-group and level of education for males and females respectively.

Cell sizes ranged from 20 females aged who had completed Year 12 only to males aged who had completed Year 11 or less , the average cell size was Table 5 shows the cut-points for the weighted means, SDs, 20th, 40th, 60th and 80th percentiles for males and females by age-group.

The quintiles and means are relatively stable for younger age-groups but start to decline between ages For all sub-groups, the upper bound of the lowest quintile is slightly higher than 1 standard deviation below the mean between 3. Discussion The SDMT is a widely used neuropsychological instrument which assesses divided attention, perceptual processing speed, visual scanning and memory Strauss et al.

The aim of this study was to report nationally representative normative data for the SDMT in a large sample, separately by gender, with a broad age range, narrow age groups and four levels of educational attainment. Our results indicate that the SDMT is significantly associated with age, gender, education and health. There was a strong non-linear effect of age, and the linear regression estimates did not support the reporting of norms for age bands wider than 5 years.

For those aged 30 years and older, the association between educational attainment and SDMT scores was stronger for males than for females, but this was not the case for the youngest age groups. This is likely to reflect the greater access to higher education for women from younger cohorts.

Interestingly, self-reported limitations with fingers or hands, difficulty gripping objects and other physical impairments did not predict performance on the SDMT, despite requiring written responses. One explanation for this finding is that performance on the SDMT is primarily underpinned by central cognitive processes as intended rather than peripheral fine-motor function.

Although participants with self-reported mental illness, nervous conditions, or other health conditions requiring treatment or medication were not excluded, these participants generally performed worse compared with those without such long-term health conditions.

Our findings suggest that the presence of a common psychiatric disorder may result in an average performance deficit of three symbol-digit pairings. Nevertheless, all three of these factors were independently associated with significantly poorer performance. In fact, the presence of a speech problem was one of the strongest predictors of lower SDMT scores, and was associated with a loss of approximately half a standard deviation.

It is possible that speech problems mask unobserved disadvantage. The finding that Indigenous Australians and those with non-English speaking backgrounds tended to perform more poorly than non-Indigenous Australians and native English speakers could be due to the language of the test administration, or familiarity and prior experience with neuropsychological testing. These cultural factors may be markers of social disadvantage and poor quality education. Cultural, cohort and personal attitudes and values may be important determinants of performance.

For example, Roivainen proposed that cross-national differences between European and American populations on speeded tasks similar to the SDMT may reflect American attitudes that value faster performance over precision. However, this explanation is countered by the numerous longitudinal studies that have consistently demonstrated intra- individual change in substitution task performance over time e.

These differences likely reflect both differences in the sampled populations, and methodological differences in generating age norms. In contrast, Yeudall et al. Data on health conditions were obtained by self-report, and only conditions that were considered to be long-term more than 6 months were recorded. It is, therefore, possible that our sample includes participants with neurological conditions that are not perceived to be long-term health conditions. Although we adjust for language first spoken and Indigenous status, we have not reported norms for specific cultural groups within Australia and it is unclear how our results apply to people with non-Australian cultural backgrounds.

There remains a need for culturally, nationally and language specific norms Gonzalez et al. We were only able to analyze the written version of the SDMT and generally note the lack of published normative data for the verbal response modality, which should be expected to yield higher scores Sheridan et al. In some contexts, it may be necessary to generate norms from more specific sub-populations. In addition, compared to other norms published for the SDMT, the scope, and scale of the norms reported in this paper provide a valuable benchmark for international research with a general population and should be useful in a broad range of both clinical and research settings.

The use of weights specific to participants completing the SDMT facilitated inference about the population based on the sample as it adjusts for non-random non-response, attrition, and for mode selection effects. Finally, the large size of the HILDA Survey sample enabled the measurement of gender, age and education specific norms with a greater degree of precision, and generalizability than was previously possible.

The findings and views reported in this paper, however, are those of the authors and should not be attributed to either DSS or the Melbourne Institute. The data are available for research purposes under license. I Intercept Activity engagement is related to level, but not change in cognitive ability across adulthood.

Psychology and Aging, 27 1 , Archives of Clinical Neuropsychology, 22 5 , Gender differences in cognitive abilities: The mediating role of health state and health habits. Intelligence, 32 1 , Journal of Clinical and Experimental Neuropsychology, 33 4 , Neuropsychological Assessment 4th ed. MacDonald, S. Pena-Casanova, J. Blesa, R. Archives of Clinical Neuropsychology, 24 4 , Intelligence, 38 1 , Miller, E. Longitudinal psychomotor speed performance in human immunodeficiency virus- seropositive individuals: impact of age and serostatus.

Journal of Neurovirology, 16 5 , The processing-speed theory of adult age differences in cognition. Within a second time limit the subject is mean of Participants reported required, consulting the key as necessary, to insert the numbers normal or corrected-to-normal visual acuity and no history of associated with the symbols.

The test can be administered in both medical disabilities. Seven days before scanning, all participants written and oral modalities. Nowadays, this task is used to assess completed the BRB-N [13] commonly used to assess cognitive cognitive impairment in a wide range of neurological and neuropsy- impairment in MS patients.

An informed consent was obtained chiatric disorders, especially multiple sclerosis MS. Indeed, the from them all, and they were monetarily rewarded 50 D for their SDMT has been included as a part of different neuropsychologi- participation in the study.

Trying to surpass condition. Both conditions were alternately presented up to a some of these drawbacks, in the present study we introduced an total of 12 blocks block duration: 30 s. In each block 15 stim- adaptation of this task that is closer to the oral version of the SDMT uli were randomly presented during 2 s.

This presentation pace included in the Brief Repeatable Battery-Neuropsychological BRB- was calculated taking into account the standardized normative data of the oral version of the SDMT obtained from [3], which establishes in 1. On the other hand, in order to avoid a possible E-mail address: forn psb.

Published by Elsevier Ireland Ltd. Forn et al. After realignment and unwrap- in the last 6 blocks. This strategy proved to be effective in preventing ping, images were spatially normalized to MNI coordinates by using memorization effects in a similar study [6]. Statistical analyses of the group were were recorded by a researcher located inside the scanner room.

Therefore, the required response in this adaptation of SDMT [15], then discarding any cognitive impairment. A total of 29 slices were acquired in with an increase in the activity of several portions of the frontal, the axial plane parallel to the AC—PC line from bottom to parietal and occipital lobes.

Most of these areas showed a similar top, providing coverage of the entire brain. A morphological activation in both hemispheres. Thus, the SDMT version presented here resembles the oral adap- tation of this task developed by Smith [16] and Rao [13] more than any other previous adaptation of this task to the fMRI constrains. These similarities refer to the characteristics of the stimuli, the cog- nitive demands and the kind of demanded response.

Therefore, both versions of this task might recruit similar cognitive processes. Nevertheless, the SDMT version presented here and the oral adap- tation of this task notably differs in the stimuli presentation pace. This procedural difference is largely depen- dent on inherent fMRI requirements since paced paradigms results in tighter control over and potentially reduces head motion during the scanning process [1], but might also be perceived as a potential reduction of the usefulness of this task as a measure of information processing speed, the third major cognitive component measured by the SDMT.

However, we think that testing the same subjects in this task but using different inter-stimuli intervals could surpass this limitation without compromising the fMRI-scanning process. In this regard, the inter-stimuli interval used in this initial study 2 s was determined after taking into account the standardized norma- tive data of the oral version of the SDMT obtained from [3] in healthy Fig. As can be seen the volunteers.

Accordingly, we observed that the use of this stimuli performance of this task resulted in the recruitment of a fronto-parietal—occipital presentation pace resulted in an almost perfect performance of the network, with Brodmann areas 6, 9, 7, and 17—18—19, exhibiting highest activity.

In agreement with this proposal, it should be noted that previ- ous studies trying to adapt the SDMT to the fMRI requirements were located in the inferior frontal gyrus. Finally, bilateral activa- in clinical populations used longer inter-stimuli intervals e. In summary, we presented a new version of the SDMT task that The main objective of the present study was to introduce a new might be used in an fMRI experimental setup.

This version is closer version of SDMT suitable for fMRI studies but able to provide clin- to the oral adaptation of this test performed by Smith [16] and ically relevant information. Accordingly, we tried to keep this new Rao [13] than other previous attempts. This major cognitive components involved on the performance of this strategy resulted in major differences towards previous attempts task. Finally, we have to indicate some limitations of this study. Thus, conversely fMRI scanning imply the use of an experimenter-imposed stimuli to the study of Grabner et al.

However, we pattern due to the use of faces, which visual processing is quite propose futures studies that the use of different inter-stimuli inter- different of other stimuli.

Further, in the SDMT version presented vals might allow the use of this SDMT as a suitable measure of this here, subjects were requested to perform a cognitive operation e. Second, future studies should take into account pos- matching numbers to those meaningless symbols according to a sible visual acuity disturbances not only in clinical populations, given key , which is virtually identical to that demanded in the but also in healthy subjects , since a strong relationship between original formulation of this test.

This is a critical difference with visual acuity and SDMT execution has been previously reported other previous studies trying to adapt this task to fMRI require- [4]. Neu- ropychol. Basho, E. Palmer, M. Rubio, B. Wulfeck, R. Forn, N. Ventura-Campos, A. Berenguer, V.

Belloch, M. Parcet, C. Brain Mapp. Benedict, J. Fischer, C. Archibald, P. Arnett, W. Beatty, J. Bobholz, G. Grabner, F. Popotnig, S. Ropele, C. Neuper, F. Gornai, K.

Petrovic, F. Ebner, S. Chelune, J. Fisk, D. Langdon, L. Caruso, F. Foley, N. LaRocca, L. Vowels, Strasser-Fuchs, F.



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